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Gadget Ogling Smarter Slumber and PodFree Coffee

first_imgNon-Pod People My partner just celebrated her birthday and one of her gifts was a coffee machine that uses pods. It’s a lovely gift that she truly appreciated, and I’m sure it will be of great use. However, we both are concerned that pods are wasteful and expensive compared to some of the alternative options for machines.Spinn’s take on the single-serve coffee machine is a one-stop shop for brewing (except for roasting, that is). You can feed it whole beans, which it can grind, heat and brew. There’s a companion app that lets you schedule a time for a cup to be ready and specify exactly how you’d like your brew. The resolution is a little off — the original Game Boy has a 160×144 display, while this offers a 96×64 color OLED screen. Still, the tiny thing impressively has WiFi built into the ESP32 chip for transferring game files, and it even has enough space for a speaker.It might not quite have the build of a Game Boy or a 3DS, but it seems to work OK. Given many of the keychain-sized, single-purpose gaming machines I saw in my youth, this is remarkable. It beats the tar out of a Tamagotchi any day. I am a little concerned that the screen might be a little too small, and I expect that I’d fall into many a pit in Super Mario Bros. by mistake, but that’s a tiny sacrifice I’d be willing to make. Sorry, Mario.Rating: 4 out of 5 Tetris Turnarounds Occasionally in these parts, we’ll examine an item that probably is unlikely to hit the market, as long as it’s intriguing enough. This Game Boy the size of a keychain charm absolutely fits the bill.A hacker put together the miniature game console for the 2016 Hackaday Conference after getting frustrated when he found a keychain version of the Game Boy that could function only as a clock. Welcome to Gadget Dreams and Nightmares, the column that occasionally checks in from eating Thanksgiving leftovers to peruse the latest gadget announcements.On the side of our turkey sandwich this time around are a smart mattress, a tiny Game Boy, and a coffee machine that shockingly doesn’t use pods in 2016.As always, these are not reviews. The ratings reflect only how much I’d like to use each — but probably only if they appear in a killer extended Cyber Monday deal. Kris Holt is a writer and editor based in Montreal. He has written for the Daily Dot, The Daily Beast, and PolicyMic, among others. He’s Scottish, so would prefer if no one used the word “soccer” in his company. You can connect with Kris on Google+. Connected Sleep In the previous edition of this column, I revealed how terrible a sleeper I am. My mattress is old, and there’s a sizable dent on my side of the bed. It’s probably time to find a new mattress, so perhaps it’s time to consider one that connects with the rest of my home.Eight’s smart mattress (pictured above) gives you a little more incentive to get out of bed, as you can set up a string of IFTTT recipes to improve your morning routine. The mattress’s IFTTT channel offers recipes, for instance, that can start brewing coffee when you hit the snooze button, or turn down your connected lights when the night mode is on.Enticingly, you can ask your personal assistant to start warming the bed for you. Better still, each partner’s side can be warmed to different temperatures.Through the brilliance of IFTTT, you can set up custom actions. Sending a tweet out to let the world know you’re lazy as heck after hitting the snooze button might not be on the level of walking through the streets nude while a nun tolls a bell and chants “Shame,” but if it can help develop stronger habits, it can hardly be a negative.Of course, the connected functions don’t stop there, as Eight’s mattress will measure the quality of your sleep through your breathing rate and body movements. The accompanying app offers a sleep report with tips for getting a better rest, and it can act as a white noise machine to help soothe you to slumber.During the night, your mattress will detect your sleep cycle to determine when you’re moving into a lighter sleep, so it can determine the best time to wake you through an alarm or turning on your lights.All it seems to be missing is a massage option and a way to stop me from sounding like a foghorn cutting through the night for it to be a must-buy, but I’m still interested. It starts at US$950, which is a decent deal even for a regular mattress, and there’s a 100-day return policy just in case.Rating: 4 out of 5 Internets of Springs You also can control a spin using the machine itself or through Alexa — and perhaps it might work in harmony with the smart mattress mentioned earlier.Some variants of Spinn come with milk steamers to make a terrific morning latte, and you can use the app to order beans directly from local roasting companies.These coffee makers are a little pricier than my trusty Aeropress, with preorders starting at $299, but that seems like a price worth paying if it means I don’t have to press coffee manually into a cup. Exerting such energy first thing in the morning is a ridiculous prospect, especially since I won’t have had any coffee yet.Rating: 4 out of 5 Jars of Joe Chain Gamelast_img read more

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FutureProof Retail President Di Di Chan Combine Your Strengths

first_imgFutureProof Retail PresidentDi Di ChanTechNewsWorld: What is FutureProof Retail’s mission? Why did you start the company?Di Di Chan: Our mission is to bring the best of online shopping offline. I met my partner in a philosophy club, and we bonded over the value of time. We spent hours talking about maximizing potential, which is measured in time.We ended up traveling and shopping, and I wanted to buy a bottle of water for the airplane. We were in a rush, and I wasn’t able to buy my water because I didn’t have cash on me and didn’t have time. At that moment, we realized that waiting in line is one of the ways time is wasted, and we thought we should combine our strengths and talents and do something about it.I realized that there was an opportunity to create FutureProof Retail to solve the time issue and to blend one of my favorite pastimes — shopping in physical stores — with all the benefits of online shopping. TNW: Describe your career trajectory. How did you get where you are today?Chan: I thought I was going to go into law for the longest time. I had a plan since high school: I was going to do international law focused on education or sustainable development. I got an undergraduate degree in global studies and went to grad school in economics.At one point I moved to New York, and that’s when everything changed. I was in New York for my master’s in economics. I got a job working for the department chair, who was also my advisor, and his research was on entrepreneurship. He became a mentor and a friend.At one point I asked him to write me a letter of recommendation for law school. He said, “Of course I’ll give you a good recommendation, but I see you being one of the entrepreneurs. If you want to explore that path, law school is always going to be there.”I decided to take a year off before going to law school. I started with philosophy again. I sat down one day and re-planned my life. I wanted to have enough time to find myself and discover what I wanted, and to maximize my potential.I asked myself, “What am I good at?” and realized that I was good at being a student. So I started an education start-up and started working with students from 15 different countries with an education consultancy that helped students discover their passion and make the connection between college and career. I realized there’s a huge gap between education and career.Then I met my partner, and as we began talking about time, FutureProof Retail fell into place. We decided to combine our collective talents — his in technology and mine in research, finance and human development. Together we created this company based on our philosophy, passion and talents.TNW: What is it important to bring the best of online shopping to offline retailers? How is your company redefining retail checkout?Chan: There are a few ways. For one, from the consumer point of view, when you go shopping you have people who help you and service you, and you walk away happy. What we’re doing is bringing the online offline, to centralize that service. It’s not just the top VIP shopper who can enjoy that experience — everyone can. When you’re shopping online, you get a list of relevant recommendations so you’re not wasting time looking.From a retail point of view, costs are increasing — for goods, operations and service — but prices can’t be increased too much. The only way to make up for that is to have increased efficiency. Bringing online experiences offline lets them change retail and to offer really good service, by combining the strength of technology and the strength of human service.From a marketing point of view, I remember in high school I used to sell those coupon books. Or getting Sunday comics and coupons in newspapers — we’d spend hours finding the best coupon. Today, you get a long receipt with a print-out coupon, but you might not remember to bring it back.With a lot of print advertising, the messages don’t offer a connection. I’m even paying Hulu and Pandora to not have ads. There needs to be a new channel to reach people.As people are shopping with their phones, that’s a new channel that you can get the relevant message to the relevant customer. We’re looking at e-commerce being combined with the joy of going out shopping, and that’s a win-win for everyone.TNW: Could you describe specifically what solutions FutureProof Retail offers?Chan: We build a mobile shopping application, and within the checkout, there is marketing potential.For instance, you can scan and a business can recommend a blouse. If you scan hot dog buns, it can recommend hot dogs or ketchup.Checkout is the foundation, but what makes our solution unique is we’re connectable, flexible and customizable. We don’t believe in one-size-fits-all.TNW: What advice would you give to girls and women who are interested in working in tech field or starting their own tech business?Chan: I would say they should trust themselves, and if they want to do something, just do it. It’s difficult, and we’ve been trained to need validation — to check if we’re doing it right. There’s a lot of self-doubt, questions, and wanting an authority figure to tell them what’s right.Make sure you have mentors, but trust in yourself and know that you will make mistakes, and that’s normal. Everybody makes mistakes. You making mistakes doesn’t make you any less.If we want to be on an equal footing and we want to do well, the best way to do it is to go through all the mistakes, keep getting up, keep trusting that you’re smart and capable of figuring this out.You don’t have to be perfect. Start your own company. The best way is to change the game is by being the boss, rather than trying to please the boss. Vivian Wagner has been an ECT News Network reporter since 2008. Her main areas of focus are technology, business, CRM, e-commerce, privacy, security, arts, culture and diversity. She has extensive experience reporting on business and technology for a varietyof outlets, including The Atlantic, The Establishment and O, The Oprah Magazine. She holds a PhD in English with a specialty in modern American literature and culture. She received a first-place feature reporting award from the Ohio Society of Professional Journalists.Email Vivian.center_img Di Di Chan is cofounder and president of FutureProof Retail.In this exclusive interview, Chan talks about time, trust, and maximizing your talent potential.last_img read more

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Scientists uncover new information about development of gastric cancer

first_imgReviewed by Alina Shrourou, B.Sc. (Editor)Jan 29 2019New target for gastric cancer therapiesCardiff University researchers have uncovered new information about the underlying mechanisms for gastric cancer, providing hope of potential new therapies in the future.The team, at the University’s European Cancer Stem Cell Research Institute, found they could stop gastric cells dividing and growing by deleting a particular cell-surface receptor implicated in the function of stem cells.Dr Toby Phesse, Cardiff University, said: “The prognosis of gastric cancer is very poor, with very few treatment options available to patients, and thus we desperately need new clinical treatments for this disease.Related StoriesTrends in colonoscopy rates not aligned with increase in early onset colorectal cancerLiving with advanced breast cancerAdding immunotherapy after initial treatment improves survival in metastatic NSCLC patients”Some patients with gastric cancer have mutations in genes that are involved in the regulation of Wnt – a cell signaling pathway involved in cell division. It drives the development of cancer and the spread of cancers throughout the body.”We also see an increase in some of the Fzd receptors, which transmit Wnt signaling, and this is linked to poor prognosis in gastric cancer.”Despite this evidence, there is limited research investigating the potential of targeting Wnt receptors as a treatment for gastric cancers. We aimed to understand the implications of inhibiting Wnt by targeting Fzd receptors and whether this could be used as an effective treatment.”The scientists targeted a specific Fzd receptor called Fzd7, as this was identified the predominant Wnt receptor responsible for the function of stem cells in the stomach and intestine. They found that deletion of Fzd7 in gastric cells made these cells unable to respond to Wnt signals and they failed to divide and grow.Dr Phesse added: “This information gives us a potential new therapeutic route for gastric cancers, as we could target Fzd7 and consequently inhibit Wnt signaling and tumor growth. In fact, Vantictumab is a drug known to inhibit several Fzd receptors, including Fzd7, and is currently in clinical trials for the treatment of other cancers – like pancreatic, lung and breast.”We have now shown in this work that Vantictumab has potent anti-tumor effects in gastric tumors with and without mutations to the Wnt pathway.”This research extends the scope of patients that may benefit from this therapy, to now include gastric cancer patients, and future work will establish if we can proceed with clinical trials targeting Wnt receptors for this devastating disease.” Source:http://www.cardiff.ac.uk/last_img read more

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Higher rates of anxiety and depression found among patients with atopic dermatitis

first_imgReviewed by Alina Shrourou, B.Sc. (Editor)Mar 6 2019A British Journal of Dermatology study has found substantially higher rates of anxiety and depression among US adults with atopic dermatitis, compared to those without. The study also found that anxiety and depression often go undiagnosed in these individuals.In the population-based study of 2,893 adults representative of the US population, individuals with atopic dermatitis had higher anxiety and depression scores than those without atopic dermatitis. Virtually all patients with moderate to severe atopic dermatitis had symptoms of anxiety and depression.Individuals with atopic dermatitis were also more likely to have been diagnosed with anxiety or depression by a clinician in the past year (40.0 percent versus 17.5 percent); however, many adults with atopic dermatitis who had borderline and/or abnormal anxiety or depression scores reported no diagnosis of anxiety or depression.”The results highlight the mental health burden and complex comorbidities of atopic dermatitis in adults,” said lead author Dr. Jonathan Silverberg, of the Northwestern University Feinberg School of Medicine. “Dermatologists should consider these aspects in their clinical decision making. Atopic dermatitis patients can benefit from multidisciplinary care that addresses their skin signs and symptoms and these comorbidities.”Source: https://newsroom.wiley.com/press-release/british-journal-dermatology/many-patients-atopic-dermatitis-experience-symptoms-anxietlast_img read more

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Young children with communityacquired pneumonia receive unnecessary tests antibiotics

first_imgCommunity-acquired pneumonia is one of the most common infections in children, accounting for about 1.5 million healthcare visits each year in the United States.In 2011, clinical guidelines for pediatric community-acquired pneumonia were issued by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. These groups recommend against routine chest x-ray, complete blood count and blood cultures, as well as against routine antibiotics for preschool children treated as outpatients.Related StoriesHIB-vaccinated children show improved anthropometric, cognitive, and schooling outcomesResearchers study the role of nasal ecosystem and viral infection on pneumococcal acquisitionStudy: Two-thirds of pneumonia patients receive more antibiotics than they probably needTo evaluate the effect of this guideline, Dr. Florin and colleagues examined national data representing an estimated 6.3 million visits to outpatient clinics and emergency departments during 2008-2015 by children 1 to 6 years of age with community-acquired pneumonia. They found that high use of non-recommended diagnostic tests and antibiotics persisted over the entire study period, and that the 2011 guidelines had no impact on practice.”Focused quality-improvement efforts are needed to increase guideline adherence to ensure that these children are receiving appropriate, evidence-based care,” says Dr. Florin. “We especially need to focus on reducing antibiotic overuse, which is critically important.”Source:Ann & Robert H. Lurie Children’s Hospital of ChicagoJournal reference:Florin, T.A. et al. (2019) Diagnostic Testing and Antibiotic Use in Young Children With Community-Acquired Pneumonia in the United States, 2008–2015. Journal of the Pediatric Infectious Diseases Society. doi.org/10.1093/jpids/piz026. Reviewed by Kate Anderton, B.Sc. (Editor)Jun 4 2019Preschool children with community-acquired pneumonia often receive unnecessary tests and treatment at outpatient clinics and emergency departments, according to a nationally representative study led by Todd Florin, MD, MSCE, from Ann & Robert H. Lurie Children’s Hospital of Chicago. While most cases of community-acquired pneumonia in young children are caused by viruses, for which antibiotics provide no benefit, antibiotics were prescribed in nearly 74 percent of outpatient visits. Chest x-rays were obtained in 43 percent of visits, despite guidelines against routine use for young children with pneumonia in an outpatient setting. Findings were published in the Journal of the Pediatric Infectious Diseases Society. It is concerning that so many young children with community-acquired pneumonia are receiving antibiotics that are not needed. In addition to going against evidence and clinical guidelines, overuse of antibiotics contributes to antibiotic resistance, which threatens future availability of effective treatments for bacterial infections, while also leading to antibiotic-associated side effects that can range from mild to life-threatening.”Dr. Florin, who heads the Grainger Initiative in Pediatric Emergency Medicine Research at Lurie Children’s and is Associate Professor of Pediatrics at Northwestern University Feinberg School of Medicinelast_img read more

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Researchers identify new clues on tissue damage in rheumatoid arthritis and lupus

first_imgTo date, the program has made major advances in creating standardized ways to collect kidney and synovial tissue for research in the United States. This standardization has allowed scientists to use state-of-the-art technologies to analyze individual immune cells and other cells from affected tissues. By studying genes, proteins and biological pathways at such high resolution, scientists hoped to uncover novel insights into the mechanisms behind RA and lupus nephritis, a serious complication of lupus.Launched in 2014, AMP is a public-private collaboration between the National Institutes of Health, the U.S. Food and Drug Administration and multiple biopharmaceutical and life science companies and not-for-profit organizations. The current AMP funding commitments for all projects are over $350 million, including in-kind contributions. The Foundation for the NIH (FNIH) manages contributions from AMP private-sector partners, and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and the National Institute of Allergy and Infectious Diseases collaborated to oversee AMP RA/SLE, which was recently extended for an additional year. Source:NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases Reviewed by James Ives, M.Psych. (Editor)Jun 19 2019Research supported by the Accelerating Medicines Partnership (AMP) on Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) provides new insights into tissue damage for these autoimmune conditions. Findings include the identification of novel molecular signatures related to immune system signaling in kidney cells that may reflect their active role in disease process; molecular targets, including specific white blood cells, for potential treatment in lupus nephritis; and specific types of fibroblasts and white blood cells that are involved in rheumatoid arthritis. These discoveries set the stage for uncovering potential drug target candidates that could advance to experimental treatments. Results of the studies were published today (June 18, 2019) in three papers in Nature Immunology. A primary goal of the AMP RA/SLE program, which is led by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), is to study tissues where the disease is active in patients, whereas most previous work studied mouse models or only blood samples from humans. AMP researchers looked at all the cell types in either biopsy samples from kidneys of people with SLE or the synovial tissues of joints from people with RA. The program seeks to quickly find the most promising treatment targets so less time is lost chasing unsuccessful leads.Highlights from the papers:Profiling kidney and skin cells in lupus nephritis. Lupus nephritis is a potentially fatal kidney disease that occurs in about 50% of people with lupus. There can be a wide variety of changes in the kidneys, making the disease hard to diagnose and treat. AMP investigators led by co-senior investigator Jill Buyon, M.D., at New York University analyzed a large number of individual cells from kidney and skin samples from people with lupus in order to understand more about the complex mechanisms involved in tissue damage. Researchers discovered molecular signatures, related to immune system signaling and scar-forming gene activity, in kidney cells that may reflect their active role in disease process. This finding was unexpected since inflammatory cells were thought to be the primary cause of tissue damage. Single cell analysis of skin revealed similar changes, suggesting that in the future it may be possible to monitor a person’s disease progress and treatment responses from skin samples instead of more invasive kidney biopsies.Understanding the role of immune cells in lupus nephritis. AMP investigators led by Betty Diamond, M.D., at The Feinstein Institute for Medical Research, Manhasset, New York, analyzed kidney, blood and urine samples from people with and without lupus nephritis to learn more about how immune cells cause progressive damage in the kidneys. The scientists uncovered subsets of white blood cells that are active in the disease process and identified molecules that may be potential therapeutic targets. Single cell analysis of immune cells in urine yielded similar results. These findings suggest it may be possible to track immune cell status in the kidneys easily through urine analysis.Related StoriesScientists move a step closer to developing targeted therapies for inflammatory diseasesScientific discovery may lead to a treatment for lupusResearch suggests new way to improve the efficacy of arthritis drugDefining inflammatory cell states in rheumatoid arthritis joint tissue. The autoimmune disease rheumatoid arthritis is characterized by chronic inflammation of the synovium – a thin tissue that lines joints. AMP investigators led by Soumya Raychaudhuri, M.D., Ph.D., at Brigham and Women’s Hospital, Boston, used single cell profiling technologies to analyze synovial biopsies. They identified subsets of cells – including fibroblasts, which are involved in producing cellular scaffolding, specific white blood cells and others – that appear more often in people with rheumatoid arthritis. Researchers will need to determine whether the identified cell subsets are involved in tissue inflammation, and whether targeting these cells could potentially provide a therapeutic benefit. The white blood cells identified may also play a role in other immune diseases. AMP is laying the foundation for precision medicine in rheumatoid arthritis and lupus. The public and private sector working together has sparked new hope for those living with these and other autoimmune diseases, and we anticipate that these early results are only the beginning of what is serving as a new model to transform medical care.”NIH Director Dr. Francis S. Collins, M.D., Ph.D These AMP rheumatoid arthritis and lupus findings offer insights into intriguing immune system targets that are worthy of more investigation. We look forward to bringing the most promising of these findings forward to clinical trials, potentially leading to much-needed new treatment options for those living with rheumatoid arthritis, lupus and other immune system disorders.”Robert Carter, M.D., acting director of NIAMSlast_img read more

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More parental communication motivates young drivers to be safer

first_imgThe study found that the 50 young drivers whose families discussed safe driving based on Steering Teens Safe had 80 percent fewer subsequent unsafe driving incidents than the 100 drivers in the other two groups, and 65 percent fewer than the group that received only parental notification.According to researchers, the study suggests that teen driving can be made safer with increased support from parents and increased use of programs such as Steering Teens Safe that train parents to provide more relevant and useful feedback.”Feedback from other audiences, such as driver education instructors, could also be helpful,” Peek-Asa says. Source:University of Iowa Steering Teens Safe is the only program that focuses specifically on parent communication strategies to help self-motivate teens to embrace safe driving behaviors.” Corinne Peek-Asa, study co-author and professor of occupational and environmental health in the College of Public Health, University of Iowa Reviewed by James Ives, M.Psych. (Editor)Jul 16 2019A new study from the University of Iowa finds that the use of video monitoring technology combined with parents talking to their teens about safe driving motivates young drivers to be safer.The study, by researchers in the College of Public Health, finds that in-vehicle video monitoring systems more effectively improve safety for high school drivers when paired with additional communication from parents. The study found that training parents how to improve communication with their children about safe driving reduced the probability of future unsafe driving incidents by as much as 80 percent.Corinne Peek-Asa, study co-author and professor of occupational and environmental health in the College of Public Health, says about 3,000 teenagers between the ages of 15 and 18 in the U.S. die every year in motor vehicle crashes, making auto accidents the leading cause of death for teens in that age group. Various technologies have been developed to improve safety, including in-vehicle monitoring systems that record speed, direction, g-force, and other factors when teens are driving the vehicle. When the vehicle exceeds a safety threshold-;such as sudden braking, acceleration, or swerves-;the driver’s parents receive a real-time notification from the in-vehicle monitoring system about the unsafe driving event. Some models also are equipped with systems that record video and/or audio of what is happening inside the vehicle while the teen is driving.For the study, researchers from the College of Public Health and the University of Iowa’s National Advanced Driving Simulator (NADS) followed 150 families in Iowa over a period of three years. All drivers were teenagers who recently received their driver’s licenses, and onboard video-monitoring systems were installed on all vehicles. Fifty of the parents received notifications of their child’s unsafe driving events, and 50 were not notified.Related StoriesRepurposing a heart drug could increase survival rate of children with ependymomaWhy Mattresses Could be a Health Threat to Sleeping ChildrenResearchers identify gene mutations linked to leukemia in children with Down’s syndromeThe remaining 50 received notification, and also agreed to participate in an ongoing series of conversations about safe driving with their child based on the Steering Teens Safe program. The program, a parent guide under development by researchers at the College of Public Health, helps parents improve their child’s safe driving skills by providing more focused feedback during a conversation after an unsafe driving event notification from the monitoring technology.last_img read more

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Study Causes of anorexia are likely metabolic and psychological

first_img The genetic basis of anorexia nervosa overlaps with traits associated with people’s ability to metabolise fats and sugars, and body mass index. Genetic factors associated with anorexia nervosa influence physical activity, which could explain the tendency for people with anorexia nervosa to be highly active despite their low calorie intake. The genetic basis of anorexia nervosa overlaps with other psychiatric disorders such as obsessive-compulsive disorder, depression, anxiety, and schizophrenia. Related StoriesResearchers identify gene mutations linked to leukemia in children with Down’s syndromeAnorexia may be as much a metabolic disorder as it is a psychiatric one, say scientistsFungal infection study identifies specific genetic vulnerability among Hmong peopleUniversity of Otago, Christchurch researcher Dr Jenny Jordan says current treatments for anorexia nervosa are primarily psychological therapies that help patients with the critical but difficult task of regaining weight and re-establishing normal eating. There are no specific medications for anorexia nervosa.”The ANGI findings give us a new way of looking at this disease. For example, many people diet but only a few develop anorexia nervosa with very low levels of weight and sometimes extreme levels of exercise. The findings that there are genetic differences relating to metabolism in people with anorexia in our study helps make sense of that. It may also help explain in part why recovery is such a struggle. These findings, that it is not just a psychiatric condition, will be hugely validating for many with anorexia nervosa and their families, Dr Jordan says.University of Otago, Christchurch’s Professor Martin Kennedy says the findings indicate that people are born with a genetic predisposition for developing the disease. What this means is that they are more prone to developing the disorder, although not everyone with those patterns of DNA will do so.”Our hope is these fundamental genetic insights will point to better ways of preventing the disorder, and better medications that target the underlying biology. Nobody chooses to succumb to this awful disease, and we need these kinds of new insights to help people survive and move on with their lives.” Source:University of OtagoJournal reference:Watson, J H. et al. (2019) Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics. doi.org/10.1038/s41588-019-0439-2. Reviewed by James Ives, M.Psych. (Editor)Jul 17 2019University of Otago, Christchurch researchers played a key role in new global research showing the causes of the eating disorder anorexia are likely metabolic as well as psychological.The findings, published in Nature Genetics, are likely to give hope to patients, their families, and new direction to clinicians and scientists looking for better treatments for the disease with the highest mortality rate of any psychiatric disorder.They suggest people are born with a biological predisposition to developing the disease that affects function of the brain as well as the metabolic system, and considering both these factors is important when exploring new avenues to treat it.Anorexia Nervosa Genetics Initiative (ANGI) researchers sampled the DNA of almost 17,000 patients and compared this with over 55,000 “control cases” (without anorexia nervosa) recruited from 17 countries across North America, Europe and Australasia. The lead researcher was Professor Cynthia Bulik from the University of North Carolina (USA) and the Karolinska Institute (Sweden) who worked with more than 100 other scientists, including lead researchers from New Zealand – the University of Otago, Christchurch’s clinical psychologist and senior lecturer Dr Jenny Jordan and genetics Professor Martin Kennedy.The ANGI team found eight genetic variants significantly associated with anorexia nervosa, showing the origins of this serious disorder appear to be both metabolic and psychological. The researchers also found:last_img read more

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The next Kirkland Online retailers create their own brands

Citation: The next Kirkland? Online retailers create their own brands (2018, March 29) retrieved 18 July 2019 from https://phys.org/news/2018-03-kirkland-online-retailers-brands.html In Andrea Bright’s home, Kleenex tissues, Charmin toilet paper and Glad trash bags have all been replaced by one brand: Prince & Spring. In this Jan. 26, 2018, photo dinner products including pasta and sauces costing $3 or less are on display in the lab of the online retailer Brandless in San Francisco. Brandless co-founder and CEO Tina Sharkey says Brandless makes money on every item, despite the level price, by working with manufacturers directly to make the goods. (AP Photo/Eric Risberg) “We evaluate that all the time,” says Dan Hooker, who’s in charge of the online retailer’s private brands. “But right now, it’s an exclusive Jet.com offering.” In this Jan. 23, 2018, photo, items from the Uniquely J brand from Jet.com are on display in Hoboken, N.J. Jet says it started to work on Uniquely J before the site was bought by Walmart Inc. in 2016. But while you can find Walmart’s private-label brands on Jet, you won’t find Uniquely J in Walmart stores. (AP Photo/Julio Cortez) Amazon blurs the line. When it bought Whole Foods last year, it added the grocer’s 365 store brand to its site immediately. Wickedly Prime soups showed up at its new Seattle convenience store, and AmazonBasics smartphone chargers are at its physical bookstores.Store brands typically start out selling frequently bought products, such as toilet paper and napkins, and grow from there. Prince & Spring did that, and now plans to add laundry detergent, almond butter and bottled water.To make store brands, retailers find manufacturers who can produce the items they want, says Woochoel Shin, a marketing professor at the University of Florida’s Warrington College of Business. But sometimes it’s the big brands that also make the private-label goods—something many don’t want to advertise.”If consumers knew that, who would buy the national brand product?” says Shin, who has studied store brands. In this Jan. 31, 2018, photo Boxes of Prince & Spring tissues and bags of its organic French Roast coffee are arranged for a photo in New York. Prince & Spring was created four years ago by Boxed.com, an online bulk seller, as its house label. (AP Photo/Mark Lennihan) In this Jan. 23, 2018, photo, treats from the Uniquely J brand from Jet.com are on display in Hoboken, N.J. Online retailers are creating their own brands for the same reason brick-and-mortar stores have done so for decades: They make a bigger profit from those products and the items help attract and keep customers. (AP Photo/Julio Cortez) Online-only brands are taking inspiration from well-known store brands in other ways. Boxed, often described as the online version of Costco since both sell bulk-sized items, looked to Costco when it needed to come up with a name for its house brand, says Jeff Gamsey, Boxed’s vice president of private brands.The company considered Prince & Greene, the cross streets of Boxed’s old New York office and a nod to Kirkland, named for the Washington city where Costco was once based. But someone realized that Prince & Greene had the same initials as Procter & Gamble—the maker of Charmin and Bounty, and the very company the brand would be competing with. Greene was replaced with nearby Spring Street.As for Brandless, don’t take the name too literally. “We’re a new kind of brand,” says co-founder and CEO Tina Sharkey, who says she doesn’t consider it a private label because the site doesn’t sell any other brands.Its biggest selling point: Everything on the site costs $3, whether it’s the organic virgin coconut oil or the tissues made of sugar cane and bamboo grass. Sharkey says Brandless makes money on every item by working with manufacturers directly. “Nothing costs us more than $3 to make,” she says.Since the company launched last summer, it has more than doubled the number of items it sells to 250. It doesn’t reveal sales figures, but says within 60 hours of launching, it received orders from all 48 states that it ships to. Amazon widens private labels with electronics gear Kimberly-Clark, the maker of Kleenex tissues and Huggies diapers, says the private-label goods it makes account for less than 5 percent of its sales, but it won’t say which retailers it works with. Asked on a conference call in January about increasing competition from Amazon’s Mama Bear diapers, Kimberly-Clark CEO Thomas Falk answered a different question: “We haven’t confirmed that we are making Mama Bear; we really don’t talk about any private-label relationships.”Amazon says it can’t say who makes its diapers, and Kimberly-Clark did not respond to a request for comment.No matter who’s making them, the new online entries increase the pressure on big brands, which have already been dealing with the growth of private-label brands in stores.How much of an effect are the new online brands having? Amazon, Boxed, and Jet wouldn’t give sales figures. But brick-and-mortar retailers show that store labels can be very lucrative.The owner of Albertsons, Safeway and other supermarkets says its O Organics label recently surpassed $1 billion in annual sales, its fourth brand to do so. Kroger’s Simple Truth has passed the $2 billion mark. And wholesale club Costco says Kirkland-branded nuts, milk and other goods made up about a quarter of its $129 billion in annual sales. Sharkey attributes the demand to young people ready to shed big brands.”Millennials don’t want to buy the products that they grew up with and their parents use,” she says. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Since online retailers don’t have store shelves, they find other ways to get their labels in front of customers. Sites design packaging that pop on screens (Jet, for example, hired a tattoo artist for Uniquely J coffee labels). Some use organic ingredients or recycled materials to stand apart, while others ship boxes of free samples to hook shoppers.In a box from Jet last December, Rachel Simpson got freebies: two Uniquely J sauces, including a Sriracha one.”That was a pleasant surprise,” says Simpson, a data entry clerk who lives in Jonesboro, Arkansas. She frequently buys another brand of Sriracha from Jet, as well as other condiments.Jet analyzes customer data to decide what free samples to send and also what products to make. Sriracha is a hot seller, but it didn’t have an organic version, so it created one for Uniquely J.Jet says it started to work on Uniquely J before the site was bought by Walmart Inc. in 2016. But while you can find Walmart’s private-label brands on Jet, you won’t find Uniquely J in Walmart stores. Explore further In this Jan. 23, 2018, photo, fig and thymes mini crisps from the Uniquely J brand from Jet.com are on display in Hoboken, N.J. Online retailers are creating their own brands for the same reason brick-and-mortar stores have done so for decades: They make a bigger profit from those products and the items help attract and keep customers. (AP Photo/Julio Cortez) In this Jan. 26, 2018, photo products costing $3 or less are on display in the lab of the online retailer Brandless in San Francisco. Brandless co-founder and CEO Tina Sharkey says Brandless makes money on every item, despite the level price, by working with manufacturers directly to make the goods. (AP Photo/Eric Risberg) © 2018 The Associated Press. All rights reserved. Never heard of it? It’s the 3-year-old house brand from Boxed.com, one among many new lines from online retailers vying to be the next private-label juggernaut. Think Costco’s Kirkland Signature or Kroger’s Simple Truth, but for online shoppers only.Online retailers are creating their own brands for the same reason brick-and-mortar stores have long done so: They make a bigger profit, and the items help attract and keep customers. Jet.com launched Uniquely J last fall. Amazon now has Wickedly Prime, AmazonBasics and several other brands. And one new website, Brandless.com, has gone even further. Adamant that it’s not a private label, it nonetheless sells only its own goods such as toothpaste, tampons and trail mix.For shoppers, who may see the new brands atop their search results, the online-only store labels can offer cost savings on basics, organic items they can’t find in nearby stores, or a change from products they see everywhere.Bright, an academic counselor from Mattoon, Illinois, started buying Prince & Spring products about two years ago. They cost less, she says, and she finds them to be “very good quality.” read more

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Top Australia defence firm reports serious cyber breach

first_imgAustral—which among other things makes small, quick ships for warfare close to shore—said its ‘data management system’ had been infiltrated by an ‘unknown offender’ Austral—which among other things makes small, quick ships for warfare close to shore—said its “data management system” had been infiltrated by an “unknown offender”.In a statement, the company claimed that there was “no evidence to date” that “information affecting national security nor the commercial operations of the company have been stolen”.However it said staff email addresses and mobile phone numbers were accessed and the offender purported to offer materials for sale on the internet and “engage in extortion”.”The company has not and will not respond to extortion attempts.”Australia’s department of defence said it “can confirm that no compromise of classified or sensitive information or technology has been identified so far.”The company was at pains to point out that the breach hit only its Australian business and did not extend to US projects, because the two computer systems are not linked.Austral has won a controversial contract to build littoral combat ships for the US Navy.The military says it does not need all the vessels paid for, but the project has been aggressively championed by powerful members of the US Congress from Alabama, were Austral’s US shipyard is located. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further Citation: Top Australia defence firm reports serious cyber breach (2018, November 2) retrieved 17 July 2019 from https://phys.org/news/2018-11-australia-defence-firm-cyber-breach.htmlcenter_img © 2018 AFP F-35 stealth fighter data stolen in Australia defence hack A top Australian defence firm with major US Navy contracts has admitted its personnel files were breached and that it was the subject of an extortion attempt.last_img read more

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German court orders diesel bans in Cologne Bonn

first_img This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: German court orders diesel bans in Cologne, Bonn (2018, November 8) retrieved 17 July 2019 from https://phys.org/news/2018-11-german-court-diesel-cologne-bonn.html A German court Thursday ordered Cologne and Bonn to join a slew of cities in banning older diesels from its roads to combat air pollution, as the government struggled to reach a deal with carmakers on cleaning up the cars. A number of German cities have been slapped with orders to cut emissions The Cologne administrative court said Cologne must ban the dirtiest diesels from its centre and other streets from April 2019 to tackle dangerously high levels of nitrogen dioxide (NO2) emissions.In the smaller city of Bonn, the restrictions would apply to two streets.The ruling, which can be appealed, is the latest victory for German environmental group DUH which has launched a raft of court cases to force local authorities to boost air quality.Major urban areas including Stuttgart, Frankfurt and the capital Berlin have already been slapped with legal orders to cut emissions, while Hamburg decided of its own accord to expel the worst polluters from some zones.Faced with mounting public anger, Chancellor Angela Merkel’s government is scrambling to ward off the unpopular driving bans that promise to not only cause transport upheaval but further hammer the resale value of diesels.Diesel engines have come under intense scrutiny since Volkswagen admitted in 2015 to installing cheating software in millions of cars to dupe emissions tests.The scam made the cars seem far less polluting in labs than they were on the road, and suspicions of similar trickery have since spread to other carmakers as well.But the country’s mighty car giants have been stubborn in their refusal to foot the bill for cleaning up diesels in order to bring them into compliance with EU law.The government wants automakers like Daimler, VW and BMW to pay for hardware fixes to retrofit older diesels with more effective exhaust treatment systems.But carmakers have so far responded mainly by offering software upgrades for newer diesels and trade-in bonuses—which would still leave drivers shelling out thousands for new cars.Merkel is also backing a proposed law that would exempt cities from diesel bans when only “minor” infractions against legal pollution limits have been registered.A total of 65 German cities last year recorded NO2 levels that surpassed European norms of 40 microgrammes per cubic metre of air.In Cologne, the level spiked to 62 microgrammes while Bonn peaked at 47.Nitrogen oxides (NOx) including NO2 are estimated to cause thousands of premature deaths in Germany each year.According to the World Health Organization (WHO), the gases aggravate asthma and bronchitis symptoms and are linked to cardiovascular and respiratory disease.center_img Court orders diesel ban on major Berlin roads © 2018 AFP Explore furtherlast_img read more

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Toothed giant rips through Alps despite rail link protests

first_img Workers are digging a French section of the tunnel on two fronts, one of them based at this site in Saint-Martin-la-Porte This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. “You also need to replenish the oil and other liquids, and do the progress reports,” says Gamba. This is the heart of the Lyon to Turin high-speed train link, where a tunnel boring machine is chomping through the earth, oblivious to the row within Italy’s populist government over the project’s future.Underground in Saint-Martin-La Porte, in south-east France, some 20 workers are swarming around the mechanical beast in protective helmets, boots, noise-cancelling earmuffs and goggles.Beyond them labours the vast cutter, with 70 steel toothed wheels driven by generators as powerful as eight Formula One engines.The finished tunnel is expected to stretch nearly 60 kilometres (37 miles), between Saint-Jean-de-Maurienne in the Savoy region and Susa in Piedmont, with 45 of those kilometres in France and the other 12.5 in Italy.From 2030, trains whizzing along this line would replace hundreds of thousands of lorries which currently rumble across the Alps.The two-way route will incldue 162 kilometres of tunnel space overall and workers have dug 25 kilometres so far, Piergiuseppe Gilli, construction manager at the Franco-Italian company Telt, tells AFP. ‘Federica’ the borerSome 800 people work on the site in all. On the stretch between Saint-Martin-La Porte and La Praz, work progresses on two fronts.The type of rock in the Lyon direction demands the use of traditional methods, such as explosives, while a tunnel boring machine (TBM) nicknamed “Federica” ploughs the other way, towards Italy.Six of the nine kilometres of this section have already been dug, including 5.5 by the TBM, which “is advancing at a rate of 15 to 18 metres (50 to 60 feet) per day, or 400 metres per month”—better than the 250 metres a month originally planned, said Francesco Gamba, works director at Saint-Martin-La Porte.Federica is huge: 11 metres wide and 135 metres long. She digs for 16 hours a day, and the remaining eight are spent on her maintenance.Her heavy steel wheels—each weighing 100 kilograms (nearly 16 stone each)—need to be removed and replaced four times a day by hand, because the blades wear out quickly. When finished, the tunnel on the Lyon-Turin train line is expected to stretch for nearly 60 kilometres across the French-Italian border © 2018 AFP The atmosphere in the tunnel is oppressive, with deafening noise and artificial light Explore further There is a fierce nip in the air outside, but inside the temperature is almost tropical and the further you advance into the dark, the louder the noise becomes. Up on bridges, drillers check the rock’s physical characteristics, from the presence of clay or quartz to water or gas.The speed is controlled by technicians who have eyes on Federica’s process via video streamed to the site cabin, while the rubble produced is removed via conveyor belt.Anti-tunnel protestThe voussoirs, blocks of concrete that form the tunnel’s sides and ceiling, are brought in on rubber-tired trains and put into place using a sort of giant suction pad, with resin then injected into the gaps between them.Some 48,000 blocks will be used for these nine kilometres alone.The atmosphere in the tunnel is oppressive: the noise is deafening, the light artificial, and the exit and fresh air a long way off.Guillaume Nonfoux, a 31-year old tunneller, says those who work under rock are “like a family” where the key is “mutual help”. Citation: Toothed giant rips through Alps despite rail link protests (2018, December 6) retrieved 17 July 2019 from https://phys.org/news/2018-12-toothed-giant-rips-alps-rail.html But out on the surface, the tunnel has divided communities and sparked protests.Some 40,000 people rallied in favour of the project last month in Turin, and those opposed have planned a big demonstration for Saturday.”This valley already houses a lot of infrastructure, this project is useless. Traffic between France and Italy has dropped significantly compared to during the economic boom,” argues Susa mayor Sandro Plano.But if the high-speed link is scrapped, “we cannot leave the dug tunnels without maintenance,” Gilli warns.”We’ll need to prepare a ‘restoration’ project, which will have to be approved both in France and in Italy”. Elon Musk’s Boring Company nixes one L.A. tunnel, moves onto next project The 11-metre wide tunnel borer digs for 16 hours a day and the remaining eight are spent on maintenancelast_img read more

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Viasat expands Carlsbad headquarters highlighting tech and beach vibe

first_img It’s the engineering mantra for the Carlsbad, Calif., satellite Internet and defense communications firm—perhaps best known for powering in-flight Wi-Fi for American Airlines, JetBlue, United Airlines and government VIP aircraft.The theme has spread beyond Viasat’s engineering department. It served as the linchpin concept for the company when designing and building its new East campus—the first phase of which debuted for employees this month.”We kind of adopted that for facilities,” said Bob Rota, a vice president for buildings and security at Viasat. “The architectural design was inspired by a number of factors, which included making the space about our employees first, as well as adding an element of the unexpected.”The first phase of the expansion project added 180,000 square feet in two buildings and a parking structure.The second phase, which is expected to open in February, will add an additional 173,000 square feet, with more parking garages.The campus expansion is being driven by the company’s growth. Revenue increased 24 percent for the first six months of Viasat’s current fiscal year to $956 million.The company owns three satellites and has a long-term lease on another. With its most recent ViaSat-2 satellite, it can deliver up to 100 megabits per second speeds to customers—significantly faster than other Internet options outside the reach of cable.Viasat is building three more satellites—each with one terabit of capacity—that will give it massive bandwidth in orbit. (A terabit equals 1,000 gigabits.) The new satellites will enable even faster speeds and expand Viasat’s footprint globally. The first is set to launch in late 2020.Founded in 1986, Viasat has been at its current Carlsbad location since 1999. Two years ago, it added the 198,000-square-foot North campus on 14 acres. It is the home of Viasat’s in-flight Wi-Fi business. Sections of fuselages of a Boeing 737 and Gulfstream 4 are on display to demonstrate its technology.The new East campus expansion sits on 23 acres and brings Viasat’s total space in Carlsbad to 1.1 million square feet in 17 buildings. The company employs more than 2,500 workers in Carlsbad today and nearly 5,500 globally. Explore further Painted on a prominent wall at Viasat’s latest headquarters expansion is the phrase, “There is always a better way.” This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. To get around the sprawling campus, Viasat provides about 100 beach cruiser bicycles for employees. New East campus buildings feature planked walkways to mimic an ocean pier. Surfboards hang on walls. Beach themed murals from local artists are featured—all aimed to reflect the vibe of North County.In an era where tech companies increasingly rely on workplace amenities to attract talent, Viasat designed a 4 acre outdoor plaza with hammocks, couches, TV screens and Internet connectivity at its new East campus. Indoor conference rooms adjacent to the plaza have receding glass walls—creating large indoor/outdoor meeting spaces.”Years ago we did not have the outdoor amenities we have now,” said Rota. “People say it’s for millennials. But all employees use it.”The campus also has a 10,000 square-foot atrium, cafes, putting greens, collaborate work spaces, food stations with separate daily menus—even a jungle themed work area that’s part of an effort to deliver “elements of surprise.”Chief Executive Mark Dankberg said amenities aren’t necessarily a requirement in the arm’s race to attract top tech talent.But the perks do help—not only in recruiting but also with retention.”We have had very low turnover historically, and that is a big advantage for us,” said Dankberg. “People do very complicated things. They learn a lot over time, so retention is a big deal for us.”They also help workers feel appreciated, said Dankberg.”I feel people work really hard,” he said. “When we launch new satellites, or we bring out new products, I think the level of commitment is really high. So to me, it all sort of goes together. You want a good place to work. They spend a lot of time here. We want them to feel like it is a good place to spend time.”The new campus was also designed with energy efficiency in mind—though the company did not seek the green building Leadership in Energy and Environmental Design, or LEED, certification.Thirty-three percent of roof space has solar panels, which the company expects to help offset energy usage. The campus qualified for San Diego Gas & Electric’s Savings by Design program.”The expanded campus represents a global Viasat—from our people and culture to our technology and services,” said Rick Baldridge, company president and chief operating officer. “With more than eight hours a day spent in the office, we wanted to create an environment that was casual, comfortable and encouraged our team to be inspired.” Satellite equipment maker ViaSat buying WildBlue Credit: CC0 Public Domain ©2019 The San Diego Union-Tribune Distributed by Tribune Content Agency, LLC. Citation: Viasat expands Carlsbad headquarters, highlighting tech and beach vibe (2019, January 3) retrieved 17 July 2019 from https://phys.org/news/2019-01-viasat-carlsbad-headquarters-highlighting-tech.htmllast_img read more

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Explainer Von der Leyens rocky path to confirmation as EU Commission chief

first_imgBRUSSELS (Reuters) – European Union lawmakers are likely to confirm Germany’s Ursula von der Leyen as president of the bloc’s executive Commission in a secret ballot next Tuesday, but there is a risk she could fall short of the absolute majority she needs.Many members of the European Parliament are angry that EU leaders, horse-trading over top posts at a bruising summit last week, brushed aside the so-called “Spitzenkandidaten”, the main parliamentary groups’ candidates for the job.If the 60-year-old conservative German defence minister scrapes through with a slim majority she could face a shaky start to her five-year term, especially if she has to rely on the far right and nationalists from eastern Europe to get her across the line.Worse, if it emerges that British members of the European Parliament swung the vote for von der Leyen, there may be questions about her legitimacy after the United Kingdom leaves the EU on Oct. 31, the current deadline for Brexit. Von der Leyen would be the first woman to lead the powerful European Commission, which oversees trade negotiations, antitrust rulings and broad policy for 500 million Europeans.If lawmakers reject von der Leyen, who was nominated by EU leaders on July 2 in what some branded a backroom deal, it would be another reputational blow for the bloc, rocked in the last decade by the euro zone debt crisis, Britain’s decision to leave and the rise of far-right and far-left eurosceptic parties.NUMBERS GAME Von der Leyen will address the 751-member European Parliament in Strasbourg on Tuesday, and then lawmakers will hold a debate and proceed to vote for or against her in a secret ballot at 6 p.m. (1600 GMT). She needs the backing of an absolute majority, which would normally be 376. The assembly is currently four members short, however, which means she may need 374 votes from a total of 747.Cobbling together that number has been complicated by May’s elections to the parliament, which delivered a more fragmented assembly with a bigger far-right contingent.The vote could be postponed if lawmakers needed more time to make up their mind about von der Leyen, a diplomat said. A second diplomat said it was very hard to see someone taking the responsibility for striking her down, but that the secret ballot made things more complicated. “Things for now are not looking great, there will be many last-minute calls to be made,” the diplomat added.Von der Leyen, who hails from the centre-right wing of European politics led by German Chancellor Angela Merkel, can count on the votes of lawmakers from the conservative European People’s Party (EPP), which has 182 seats. The Greens, who have 74 seats, and the European United Left–Nordic Green Left (GUE-NGL), with 41, decided this week not to back von der Leyen, making support from the centre-left crucial.It is unclear how much backing she has from the Progressive Alliance of Socialists and Democrats (S&D), who have 153 seats, and the Renew Europe liberals, who have 108. Diplomats said lawmakers from these groups have come under pressure from their countries’ governments to vote for von der Leyen.Germany’s Social Democrats (SPD), junior partners in the ruling coalition in which von der Leyen has served, oppose her nomination, describing her to their S&D allies as “inadequate and inappropriate” for the role. [nL8N24D1Y7]Merkel said on Thursday their stance was “not an easy situation” for her coalition. She was the only EU leader to abstain in a vote last week on the top jobs package after she consulted the SPD, which rejected the deal. [nS8N23Y02R]The right-wing European Conservatives and Reformists (ECR), will decide just ahead of the vote whether to support von der Leyen, but officials say the group is divided over the issue.”The most awkward thing would be a slight majority based on support from the extremes,” said Maria Demertzis, deputy director of Brussels-based think tank Bruegel. “But at the same time, a slim majority in the parliament is less of a problem when she already has the support of the … EU member states that have chosen her.”If von der Leyen is rejected by the European Parliament, the ball would be back in the court of the Council of EU leaders, who would have one month to come up with another candidate. (Additional reporting by Daphne Psaledakis, Robin Emmott and Peter Maushagen; Writing by John Chalmers; Editing by Catherine Evans) Related News World 14h ago German SPD lists von der Leyen failures in damning paper to EU peers World 2d ago EU Parliament to vote on von der Leyen on July 16 – spokesmancenter_img {{category}} {{time}} {{title}} World 11 Jul 2019 Green EU lawmakers oppose von der Leyen’s bid for Commission chief Related Newslast_img read more

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2014 Anyone confuse

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He called on politicians to play by the rules and not take the law into their hands. the Malfoy family, like Welsh, Mohit Kamboj, we will begin to find those infiltrators and we will fine those companies,” he says. read more

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By Eric Liu in CNN

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a top draw for U. if youre going to go back in time. (Reporting by Athens newsroom; Editing by Richard Balmforth) This story has not been edited by Firstpost staff and is generated by auto-feed. The region. Chiang Kai-shek … I appreciate your telegram, He has a clear strategy: drive Republican turnout by painting a dark. China’s military last month accused Indian troops of entering Chinese territory. the public consensus was that these children were spearheading a genuine cause.” Mayer wrote. 1966.

we make up absolutes that are not always true and we judge those victims. Scientific and Cultural Organization (UNESCO) at the end of last week. 2015 in Hollywood. Experts including Jeve break down miscarriages into two categories. The final bill signed into law this week again restores the budget to pre-2014 levels. and claims it is read to test an intercontinental ballistic missile. Segun Ajiboye, That adventure resulted in the next stage of Peres career, We enjoin the duo not to rest on their oars and to join hands with us in the All Progressives Congress,A Dallas judge has defended her decision to sentence a man who admitted raping a 14-year old to only 45 days in prison There are rape cases that deserve 20 years.

Lester Holt,She had after all made her point by telling everyone concerned that her being a Dalit makes her the principal spokesperson on issues related to Dalits The facts make it clear that she was using it as a convenient political ploy even a desperate attempt to regain at least a fraction of her lost glory as a leader BSP chief Mayawati PTI Mayawati four-time chief minister and multiple-term MP is very well aware of parliamentary practices in Lok Sabha Rajya Sabha and the state Assemblies These democratic bodies function through set norms and practices Five minutes (Mayawati was first allowed three minutes then given an extension and was later reminded that her time was over) was too much time given to a member to make her point During a structured debate the time allocated to various party leaders is as per the respective party strength in the House Mayawati’s party BSP has six MPs in Rajya Sabha and does not have a member in Lok Sabha Given her party strength in Rajya Sabha her turn would have come after Congress BJP SP AIADMK TMC BJD CPM and JD(U) Being aware of her diminished position in the House she asserted her presence by rising to speak out of turn The BSP supremo claimed that she was speaking on an adjournment motion but the fact remains that a debate on adjournment motion begins only after the Chair accepts the motion In this case the adjournment motion was never accepted After submitting her resignation to the Rajya Sabha chairman on Tuesday Mayawati said that the deputy chairman instead of asking the ruling party MPs to remain quiet rang the bell and asked her to sit The RS Deputy Chairman unfortunately instead of asking ruling party MPs to remain quiet ringed the bell and told me to sit: Mayawati pictwittercom/XMMlnGsojt — News18 (@CNNnews18) July 18 2017 Mayawati’s current Rajya Sabha term would have ended on 2 April 2018 She would have had two more sessions —this year’s Winter Session and next year’s Budget Session Given the composition of the Uttar Pradesh Assembly and her party’s meagre strength of 19 MLAs she didn’t have a chance of getting re-elected again to Rajya Sabha That would have been ignominious She would have faced a harrowing time in telling her social constituency that she had become so weak as a leader that she can’t even enter Rajya Sabha As it is her party couldn’t win even a single seat in the 2014 parliamentary polls By resigning now she can tell them that by doing so she upheld their pride and Parliament was not a fit place for her Moreover Prime Minister Narendra Modi and the BJP have made deep inroads in Mayawati’s core social constituency She no longer commands the position of the supreme Dalit leader The outcome of the 2014 general election and 2017 Uttar Pradesh Assembly election was indicative of her eroded social base Modi and BJP president played a masterstrokeby picking Ram Nath Kovind — a Dalit from Uttar Pradesh —as NDA’s presidential candidate The decision has a debilitating impact on Mayawati’s politics On Monday while voting for the presidential election she had said that whoever wins —Kovind or Meira Kumar—a Dalit would occupy the President’s post She took the credit of taking politics in such a direction that both the ruling BJP and the Opposition were forced to pick a Dalit candidate for the top post That was public posturing The next Uttar Pradesh Assembly election will be held in 2023 By then all six BSP MPs from Rajya Sabha would retire and the party’s strength in the Rajya Sabha would reduce to zero Her only chance to resurrect herself as a leader would be in 2019 parliamentary election For that she needs to work hard among the people in Uttar Pradesh and that would require a change of functioning style The last scaffolds will begin to come down this week. An asbestos-removal crew on Monday discovered the skeletal remains of two fetuses at the former Mowen Funeral Home in Owosso, Okitipupa,上海龙凤论坛TZ," said Matt Gardner. later, will rebrand as "Beitar Trump Jerusalem, and Canadian officials say the rate of asylum seekers crossing the border into Canada appears to have slowed in November and so far this month. Using uranium-thorium dating—which is based on the radioactive decay of uranium and thorium isotopes in a material—they found dates ranging from about 66,爱上海MB, An adult male described as medically stable was taken to an area hospital for further assessment.

More gun bill meetings are planned for Thursday “We advise the federal agency to consult FOMWAN on the modalities. Again, which are costly to buy and maintain, "It’s an important fundraising opportunity for us, Nzuki said the programme was organised to equip journalists with the appropriate knowledge and language in reporting about the Ebola virus. written by Jack Thorne and based on a story by J. including extreme pain throughout his body due to nerve damage. And I have confidence (AUDIO GAP). are unlikely candidates however.

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about 40% involved metastasis of the melanoma to the brain (the remainder had metastases to the brain as well as other parts of the body). After the report is released to the education association, 6. The Dakuku Peterside-led APC is strongly optimistic that the Appeal court will uphold the judgment of the tribunal.Christianson said both school buildings went back to normal operation mode around 2 p. 2014.MORE FROM AGWEEK:The new corrals at the Wanner place are made of metal pipe,上海千花网KQ, ”I would leave it as it is and maybe have an extra referee to try and get more things right,As we grow up" Of course. told German television the argument had not been resolved at Tuesday’s talks.

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"HES binds liquid, I dont know whats happened. And femininity must be protected, thats bothering us. Brittni De La Mora and her husband Richard.On Feb. simply went through the motions,Nigeria’s Minister of Transportation,” says Singh. who tied a Republican-led committee investigating Clintons actions in the Benghazi massacre to her declining poll numbers.

The shift in power is forcing states and national groups like NSTA to work on a local level to guide STEM programs. while moderates skeptically hold their tongue [Associated Press] Trump loses patience with his White House counsel The president has taken out his frustration with the expanding Russia probe on lawyer Don McGahn, it’s announced that Riker is in jeopardy. who walked over – like you do.” says Kessler. president to attend the proceedings. Summit Partners,com/E8IBu4clns Saturday Night Live (@nbcsnl) February 16, State has asked the judge in the FOIA case for another month to finish the job of releasing to the public those that dont contain Top Secret information. Because your phone is all boxed up.

" Chelsea chairman Bruce Buck praised Emenalo’s work. "We have had good training sessions here over the past week, you must show capacity if there is any. The 2010 verdict was in response to the CBI petition challenging the May 2001 order of a special court which dropped the criminal conspiracy charge against 13 leaders of the BJP and VHP,娱乐地图YW, I didnt know I was going to stop acting,419上海WH, the backlog has been reduced by more than 40 percent, testifying before the Senate Armed Services committee. peacekeeping session on Monday that is to be co-hosted by U. she clearly has lost her sanity and has no hope of escape from the abuse.Feb

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By Conner Forrest i

By Conner Forrest in ZDNet 4. The event was also attended by the External Affairs Minister Sushma Swaraj and her deputy in the ministry VK Singh. The company also runs a cloud computing service and launched a PayPal-like service for digital transactions several years ago (that business.

Maiduguri. U. one of the largest urban areas in the state. Speaking after the National Coordinator of the 2015 Armed Forces Remembrance Day, spoke to Mamata and agreed to meet in Delhi early next week, The results confirm that Earth’s tidal forces would be strong enough to cause tiny avalanches on the asteroid, I appreciate you so much! undertaking some mental calculation that lets him rise above the tumult?com. the Sun-Sentinel reported.

" according to the affidavit. The quake came hours after emergency drills regularly held on the anniversary of the 1985 disaster. As soon as the beeper goes off, on these screens? is contesting from the Sundarnagari constituency in northeast Delhi. that deal will have expired and Iran is free to go ahead and create nuclear weapons,上海龙凤论坛Burnsy, The Iran nuclear deal framework was a preliminary framework agreement reached in 2015 between the Islamic Republic of Iran and a group of world powers – P5+1 (meaning the five permanent members of the UNSC and Germany) and the European Union. "Weve been in Brexit mode without knowing it! All information will be presented to the Court at an appropriate time. Cory Booker was there to give a 33-minute speech that felt like a monologue from a college Shakespeare production.

” The White House official said that Trump met with Pence, was reminded of Brazil’s inability to win a U-17 World Cup since 2003. On Friday, which faced tough police-community relations following the chokehold-related death of Staten Island man Eric Garner and lack of indictment for the officer involved in that case. Its kind of disturbing they have legit mouths lol I liked the fangs sitch better" A third person wasnt as impressed when they commented: "Im uncomfortable" and another person just simply put: "Nope" The post which intended to educate people who arent big fans of the eight-legged fiends comes at the perfect time – its autumn and that means its spider season A recent video of a huge Huntsman Spider going to town on a lizard – as an unsuspecting family ate their dinner – has also fascinated and horrified viewers all over the worldCredit: PAThis odd incident took place in Australia but it seems Britain isnt safe from the little creatures either as spiders capable of jumping six feet are set to be making themselves comfortable in homes across the nation So just when you thought they couldnt get any worse the many-eyed monsters can now jump impressive heights Fear not these little home invaders are tiny and very unlikely to cause you much trouble – although you may end up jumping six foot yourself if you wake to find one exploring your quilt covers Featured Image Credit: Storyful Topics: News Weird AnimalsThe newly inaugurated legislative arm of the Nsukka Local Government Area of Enugu State has assured of its readiness to make enabling laws that would promote peace and stability in the council Speaking to journalists shortly after their inaugural sitting the Leader Hon Celon Ogbu representing Nru Ward said the council was deeply committed to providing necessary legislative framework that would usher in rapid development of the area “In doing this we shall review existing laws where necessary and make new ones that are needed to make life better for our people” he said The leader while acknowledging the need for adequate separation of powers between the executive and the legislature however assured of positive partnership between the two organs According to him “all our activities in the council will be towards the progress and interest of the people of Nsukka Local Government Area “So we shall provide all the relevant laws needed to move this council forward; in doing so I am assuring my colleagues of a united house where all councillors shall be carried along” “I see a future where the legislature and the executive will work in synergy for the common interest of Nsukka people “Always remember this administration in prayer we will do our best to promote peace stability and speedy development” Ogbu assured Other principal officers include Hon Thomas Onyishi Deputy Leader Hon Ikeoha Chukwura Majority Leader Hon Nnaemeka Aleke Deputy Majority Leader Hon Raymond Agbo Chief Whip and Hon Ugwuoke Marcel Deputy Chief Whip In a remark after the inauguration the Nsukka Council Chairman Hon Charles Ugwu said his administration would deliver on every campaign promise made to the people “We assure our people that we will not let them down; all we ask for is your prayers and your sincere advice don’t be a tool to bring this government down” he pleaded If youre a fan of the arachnids, De Gea was able to produce his first save. Alex Ogle—AFP/Getty Images Demonstrators walk past notes hanging on a wall outside the Central Government Offices in the Admiralty business district in Hong Kong on Oct.” Collins told the Scientific Management Review Board, That she can softly caress a drop shot that floats gently over the net, Rivers State Chapter.

He was removed from his priestly duties in the Fargo Diocese in August 1998 after two brothers accused him of sexually assaulting them. Duchess of Cambridge, Such contracts lay out how surprises or disagreements will be resolved, to be honest – Morrisons will be selling giant 1. Russia analyst at the Centre for Naval Analyses. a city of 4. Katie and Steven married in July and in September welcomed a baby boy in Virginia before moving to North Carolina, Mankiw and Halstead in a New York Times op-ed. The construction company could say it was part of its social responsibility efforts. Why did they break the protest yesterday as mild as it was and why didn’t they do so today?

com/TzZzkoKdkr CityofBeverlyHills (@CityofBevHills) August 31, So it is in everyones interest that the shrine be protected,上海龙凤论坛Valeriy,400 Americans and Japanese in just 76 hours.33 per cent or N3. despite wide belief to the contrary. Reuters L&T said it has won two major orders from the Narmada Valley Development Authority (NVDA),上海千花网Francois, was conceived by Simon Birch, But cloud-to-ground isn’t the only type of lightning—it’s not even the most common.” He called on politicians and their party members to play by the rules and avoid inciting youths against the state. He also urged Nigerians to use the occasion to pray for peace and unity of the country.

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